Interleukin-35 plays a pivotal role in maintaining the testicular immune privilege
نویسندگان
چکیده
منابع مشابه
Contribution of IL-12/IL-35 Common Subunit p35 to Maintaining the Testicular Immune Privilege
The testis is an organ with immune privilege. The comprehensive blood-testis barrier formed by Sertoli cells protects autoimmunogenic spermatozoa and spermatids from attack by the body's immune system. The interleukin (IL)-6/IL-12 family cytokines IL-12 (p35/p40), IL-23 (p19/p40), IL-27 (p28/Epstein-Barr virus-induced gene 3 [EBI3]), and IL-35 (p35/EBI3) play critical roles in the regulation of...
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ژورنال
عنوان ژورنال: Reproductive Immunology and Biology
سال: 2014
ISSN: 1881-607X,1881-7211
DOI: 10.3192/jsirib.29.13